During ageing, collagen present in intercellular spaces becomes

Options

A. Destroyed
B. Impermeable and rigid
C. More elastic
D. All the above

Answer

**Step-by-Step Solution:**

1. **Understanding Collagen's Role**: Collagen is a crucial protein found in the intercellular spaces of tissues, providing structural support and elasticity to the skin and other organs.

2. **Effects of Aging on Collagen**: As individuals age, the production of collagen decreases, and the existing collagen fibers undergo changes. This leads to a reduction in skin thickness and elasticity.

3. **Analyzing the Options**:
- **Destroyed**: While collagen may degrade, the term "destroyed" is not entirely accurate as some collagen may still be present but altered.
- **Impermeable**: Aging collagen can become less permeable, affecting nutrient and moisture exchange.
- **Rigid**: Collagen becomes more rigid with age, leading to less flexibility in the skin.
- **More Elastic**: This is incorrect; collagen loses elasticity with age.

4. **Choosing the Correct Answer**: Based on the analysis, the most accurate description of collagen changes during aging is that it becomes "impermeable and rigid." Therefore, the correct choice is option B.

5. **Conclusion**: During aging, collagen in the intercellular spaces becomes impermeable and rigid, contributing to the overall aging process of the skin.

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