According to which theory is the given statement correct ?
Statement. B and T cells having receptors for self antigens, undergo programmed cell death

Options

A. Somatic mutation theory
B. Programmed senescence theory
C. Wear and tear theory
D. Immunological theory .

Answer

To answer the question, "According to which theory is the given statement correct? Statement: B and T cells having receptors for self antigens undergo programmed cell death," we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Statement**: The statement indicates that B and T cells, which have receptors for self-antigens, undergo programmed cell death. This process is crucial for maintaining immune tolerance and preventing autoimmunity.

2. **Identifying the Key Process**: The programmed cell death referred to in the statement is known as apoptosis, which is a form of programmed cell death that helps eliminate cells that could potentially cause harm to the body, such as those that react against self-antigens.

3. **Exploring the Options**: The options provided are:
- A. Somatic Mutation Theory
- B. Programmed Senescence Theory
- C. Wear and Tear Theory
- D. Immunological Theory

4. **Analyzing Each Theory**:
- **Somatic Mutation Theory**: This theory suggests that aging is due to the accumulation of mutations in somatic cells, which is not directly related to the programmed cell death of B and T cells.
- **Programmed Senescence Theory**: This theory posits that cells have a predetermined lifespan and undergo apoptosis when they reach this limit, which aligns with the statement regarding B and T cells and their programmed cell death.
- **Wear and Tear Theory**: This theory suggests that aging results from the cumulative damage to cells and tissues over time, which does not specifically address the programmed cell death of immune cells.
- **Immunological Theory**: This theory states that aging is associated with a decline in immune function, but it does not specifically explain the programmed cell death of B and T cells in response to self-antigens.

5. **Conclusion**: Based on the analysis, the correct answer is **Programmed Senescence Theory**, as it best explains the phenomenon of B and T cells undergoing programmed cell death when they have receptors for self-antigens.

### Final Answer:
The correct theory according to the statement is **Programmed Senescence Theory**.

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