Hangover is due to accumulation of

Options

A. Ethanol in liver
B. Ethanol in lungs
C. Acetaldehyde in body
D. Formation of formaldehyde from acetaldehyde

Answer

**Step-by-Step Solution:**

1. **Understanding Hangover**: A hangover is defined as the unpleasant physiological and psychological effects experienced after heavy drinking. It typically occurs the morning after consuming alcohol.

2. **Cause of Hangover**: The primary cause of a hangover is the accumulation of a specific substance in the body. This substance is known to be toxic and is a byproduct of alcohol metabolism.

3. **Alcohol Metabolism**: When alcohol (ethanol) is consumed, it is metabolized in the body. The enzyme responsible for the initial breakdown of alcohol is called alcoholic dehydrogenase.

4. **Formation of Acetaldehyde**: As alcohol is metabolized by alcoholic dehydrogenase, it is converted into acetaldehyde. Acetaldehyde is a toxic compound that contributes to the symptoms of a hangover.

5. **Symptoms of Hangover**: The accumulation of acetaldehyde leads to various symptoms such as dizziness, dry mouth, headache, weakness, mood changes, and dehydration. Dehydration occurs because alcohol increases urine output.

6. **Conclusion**: Therefore, the hangover is primarily due to the accumulation of acetaldehyde in the body after excessive alcohol consumption.

7. **Final Answer**: The correct answer to the question "Hangover is due to accumulation of" is acetaldehyde.

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