Which one is not correcty matched

Options

A. `B_(12)`-Pernicious anaemia
B. Vitamin `B_(6) `-Loss of appetite
C. `B_(1)`-Beri-beri
D. `B_(3)` -Pellagra

Answer

To solve the question "Which one is not correctly matched?" we will analyze each option provided in the question regarding vitamins and their associated conditions.

### Step-by-Step Solution:

1. **Analyze Vitamin B12 and Pernicious Anemia:**
- Vitamin B12, also known as cyanocobalamin, is essential for the formation of red blood cells (RBCs).
- A deficiency in Vitamin B12 leads to pernicious anemia, a condition characterized by the inability to produce enough healthy RBCs.
- **Conclusion:** This match is correct.

2. **Analyze Vitamin B6 and Loss of Appetite:**
- Vitamin B6 is also known as pyridoxine. Its deficiency can lead to microcytic anemia, but it is not typically associated with loss of appetite.
- Loss of appetite is not a recognized symptom of microcytic anemia.
- **Conclusion:** This match is incorrect.

3. **Analyze Vitamin B1 and Beriberi:**
- Vitamin B1 is known as thiamine. A deficiency in thiamine leads to beriberi, which affects the cardiovascular and nervous systems.
- **Conclusion:** This match is correct.

4. **Analyze Vitamin B3 and Pellagra:**
- Vitamin B3 is known as niacin or nicotinamide. A deficiency in niacin leads to pellagra, which is characterized by dermatitis, dementia, and diarrhea.
- **Conclusion:** This match is correct.

### Final Answer:
The option that is not correctly matched is **Vitamin B6 and Loss of Appetite**.