The deficiency of the vitamin known to cause abortion in early pregnancy of Rat

Options

A. Retinol
B. Calciferol
C. Tocopherol
D. Naphthaquinone

Answer

### Step-by-Step Solution:

1. **Identify the Question**: The question asks about the vitamin deficiency that causes abortion in early pregnancy in rats.

2. **Analyze the Options**: The options provided are:
- A) Retinol (Vitamin A)
- B) Calciferol (Vitamin D)
- C) Tocopherol (Vitamin E)
- D) Naphthaquinone (Vitamin K)

3. **Evaluate Each Option**:
- **A) Retinol (Vitamin A)**:
- Function: Vitamin A is essential for vision and immune function.
- Deficiency Effects: It primarily causes night blindness and does not have a known connection to abortion or fertility issues.
- Conclusion: Incorrect option.

- **B) Calciferol (Vitamin D)**:
- Function: Vitamin D is crucial for bone health and calcium metabolism.
- Deficiency Effects: It leads to conditions like rickets and osteomalacia, but does not directly relate to fertility or pregnancy.
- Conclusion: Incorrect option.

- **C) Tocopherol (Vitamin E)**:
- Function: Vitamin E acts as an antioxidant and is important for reproductive health.
- Deficiency Effects: A deficiency in Vitamin E has been linked to sterility and abortion in early pregnancy in rats. This was first observed in 1936.
- Conclusion: Correct option.

- **D) Naphthaquinone (Vitamin K)**:
- Function: Vitamin K is essential for blood clotting.
- Deficiency Effects: It causes prolonged bleeding and does not have a known connection to abortion or fertility.
- Conclusion: Incorrect option.

4. **Final Answer**: The vitamin deficiency known to cause abortion in early pregnancy in rats is **C) Tocopherol (Vitamin E)**.