Digestive enzyme not found in human pancreatic juice is

Options

A. Nuclease
B. Nucleotidase
C. Trypsin
D. Lipase

Answer

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks for a digestive enzyme that is not found in human pancreatic juice.

2. **Identifying the Source**: Human pancreatic juice is secreted by the pancreas and contains various digestive enzymes.

3. **Listing Common Enzymes in Pancreatic Juice**: Some of the major enzymes present in human pancreatic juice include:
- Trypsin (and its inactive form, trypsinogen)
- Chymotrypsin (and its inactive form, chymotrypsinogen)
- Lipase
- Amylase
- Nuclease
- Carboxypeptidase

4. **Analyzing the Options**: The options given are:
- Nuclease
- Nucleotidase
- Trypsin
- Lipase

5. **Evaluating Each Option**:
- **Nuclease**: This enzyme is present in pancreatic juice and helps in the digestion of nucleic acids.
- **Nucleotidase**: This enzyme is not found in human pancreatic juice. It is a hydrolytic enzyme that catalyzes the hydrolysis of nucleotides into nucleosides and phosphates.
- **Trypsin**: This enzyme is present in pancreatic juice and is crucial for protein digestion.
- **Lipase**: This enzyme is also present in pancreatic juice and is important for the digestion of fats.

6. **Conclusion**: Based on the analysis, the digestive enzyme that is not found in human pancreatic juice is **Nucleotidase**.

### Final Answer:
The digestive enzyme not found in human pancreatic juice is **Nucleotidase**.

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