Which is not a gastrointestinal hormone

Options

A. Cholecystokinin
B. Gastrin
C. Secretin
D. Cortisol

Answer

To determine which of the given options is not a gastrointestinal hormone, we will analyze each option one by one.

### Step-by-Step Solution:

1. **Identify the Options**: The options provided are:
- A) Cholecystokinin
- B) Gastrin
- C) Secretin
- D) Cortisol

2. **Analyze Cholecystokinin**:
- Cholecystokinin (CCK) is a gastrointestinal hormone. It stimulates the gallbladder to release bile and the pancreas to secrete pancreatic juice, which aids in digestion.
- **Conclusion**: CCK is a gastrointestinal hormone.

3. **Analyze Gastrin**:
- Gastrin is another gastrointestinal hormone. It acts on the gastric cells in the stomach, stimulating them to secrete hydrochloric acid (HCl) and pepsinogen, which are essential for digestion.
- **Conclusion**: Gastrin is a gastrointestinal hormone.

4. **Analyze Secretin**:
- Secretin is also a gastrointestinal hormone. It stimulates the pancreas to release bicarbonate, which helps neutralize stomach acid in the small intestine, facilitating digestion.
- **Conclusion**: Secretin is a gastrointestinal hormone.

5. **Analyze Cortisol**:
- Cortisol is not a gastrointestinal hormone. It is produced by the adrenal cortex and is involved in various functions, including the regulation of metabolism, immune response, and stress response. It does not play a direct role in digestion.
- **Conclusion**: Cortisol is not a gastrointestinal hormone.

6. **Final Answer**:
- Based on the analysis, the option that is not a gastrointestinal hormone is **D) Cortisol**.