Bile salts activate enzyme

Options

A. Pepsinogen
B. Trypsinogen
C. Lipase
D. Pancreatic amylase

Answer

### Step-by-Step Solution:

1. **Understanding Bile Salts**: Bile salts are compounds produced from cholesterol in the liver and stored in the gallbladder. They play a crucial role in the digestion and absorption of fats.

2. **Identifying the Enzymes**: The question lists four enzymes: pepsinogen, trypsinogen, amylase, and pancreatic amylase. We need to determine which of these is activated by bile salts.

3. **Pepsinogen**: Pepsinogen is an inactive enzyme (zymogen) that is converted into its active form, pepsin, in the presence of hydrochloric acid (HCl) in the stomach. Therefore, bile salts do not activate pepsinogen.

4. **Trypsinogen**: Trypsinogen is another zymogen that is activated to trypsin by the enzyme enterokinase (also known as enteropeptidase) in the small intestine. Bile salts do not activate trypsinogen.

5. **Lipase**: Lipase is an enzyme that breaks down fats into fatty acids and glycerol. Bile salts do not directly activate lipase; however, they do emulsify fats, which increases the surface area for lipase to act on. This makes lipase more effective in fat digestion.

6. **Pancreatic Amylase**: Pancreatic amylase is responsible for breaking down carbohydrates. It is activated by chloride ions, not bile salts.

7. **Conclusion**: Among the options provided, lipase is the enzyme that is most associated with the action of bile salts, as bile salts aid in the emulsification of fats, which is essential for lipase activity.

### Final Answer:
The correct answer is **Lipase**.

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