ATP = ADP ~ P hypothesis was givan by Lipman in

Options

A. 1940
B. 1950
C. 1960
D. 1970

Answer

**Step-by-Step Solution:**

1. **Understanding ATP and ADP:**
- ATP (Adenosine Triphosphate) is known as the energy currency of the cell. It consists of a ribose sugar, adenine (a nitrogenous base), and three phosphate groups.
- When ATP is hydrolyzed (broken down), it releases energy and converts into ADP (Adenosine Diphosphate) and an inorganic phosphate (P).

2. **The Hypothesis:**
- The ATP = ADP ~ P hypothesis suggests that ATP can be represented as ADP plus a high-energy phosphate group. The squiggle (~) indicates that the phosphate bond is high-energy.

3. **Historical Context:**
- The concept of ATP and its role in energy transfer was developed over time. The term "ATP" was coined by Lohmann in 1929.
- The specific hypothesis regarding the representation of ATP as ADP plus a phosphate was introduced by Lippmann.

4. **Identifying the Year:**
- According to the information provided, Lippmann introduced this hypothesis in the year 1940.

5. **Conclusion:**
- Therefore, the correct answer to the question is that the ATP = ADP ~ P hypothesis was given by Lippmann in 1940.

**Final Answer:**
The ATP = ADP ~ P hypothesis was given by Lippmann in 1940.

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