Acoording to induces conformation change in enzyme

Options

A. Substrate induces conformation change in enzyme
B. Substrate changes its shaps agter binding
C. Conformational change takes place in substrate
D. There is no conformation change in enzyme.

Answer

To answer the question regarding induced conformational changes in enzymes, we will analyze the options provided based on the induced fit theory of enzyme action.

### Step-by-Step Solution:

1. **Understanding Induced Fit Theory**:
- The induced fit theory suggests that when a substrate binds to an enzyme, it induces a change in the enzyme's conformation (shape). This change allows the enzyme to better accommodate the substrate, facilitating the catalytic process.

2. **Analyzing the Options**:
- **Option 1**: "Substrate induced conformational change in enzyme" - This statement is correct because the binding of the substrate does induce a conformational change in the enzyme.
- **Option 2**: "Change its shape after binding" - This statement is also correct as it refers to the enzyme changing shape after the substrate binds.
- **Option 3**: "Conformational change takes place in the substrate" - This statement is incorrect because the conformational change occurs in the enzyme, not the substrate.
- **Option 4**: "There is no conformational change in enzyme" - This statement is incorrect since the enzyme does undergo a conformational change upon substrate binding.

3. **Conclusion**:
- Based on the analysis, the correct understanding is that the substrate does indeed induce a conformational change in the enzyme after binding. Therefore, the option that states "Change its shape after binding" is the most accurate representation of the induced fit theory.

### Final Answer:
The correct option is: **"Change its shape after binding."**

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