What is exhibited by lower kmvalue

Options

A. More affinity with substrate
B. Less affinity with substrate
C. More affinity with Product
D. Less affinity with Product

Answer

To solve the question regarding what is exhibited by a lower Km value, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Km Value**:
- Km (Michaelis constant) is a crucial parameter in enzyme kinetics. It is defined as the substrate concentration at which the reaction velocity is half of its maximum value (Vmax).

2. **Interpretation of Km**:
- A lower Km value indicates that a lower concentration of substrate is required to reach half of the maximum reaction velocity. This suggests that the enzyme can effectively bind to the substrate at lower concentrations.

3. **Affinity for Substrate**:
- The affinity of an enzyme for its substrate is inversely related to the Km value. Therefore, a lower Km value means that the enzyme has a higher affinity for the substrate.

4. **Conclusion**:
- Based on the definition and interpretation of Km, we can conclude that a lower Km value exhibits **more affinity with substrate**.

### Final Answer:
- The correct answer is: **more affinity with substrate**.

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