Philadelphia chromosome ocurs in patients suffering from

Options

A. Leukemia
B. Rickets
C. Hepatitits
D. Albinism

Answer

**Step-by-Step Solution:**

1. **Understanding the Philadelphia Chromosome:**
- The Philadelphia chromosome is an abnormal chromosome that is formed due to a specific genetic alteration involving the translocation of genetic material between chromosome 22 and chromosome 9.

2. **Identifying the Condition Associated with the Philadelphia Chromosome:**
- This genetic alteration is primarily associated with certain types of leukemia, particularly chronic myeloid leukemia (CML) and sometimes acute lymphoblastic leukemia (ALL).

3. **Analyzing the Options:**
- The question provides four options: leukemia, rickets, hepatitis, and albinism.
- Rickets is a condition caused by vitamin D deficiency and is unrelated to chromosomal abnormalities.
- Hepatitis is a liver condition and does not involve the Philadelphia chromosome.
- Albinism is a genetic condition characterized by a lack of melanin and is not associated with the Philadelphia chromosome.

4. **Conclusion:**
- Based on the information, the Philadelphia chromosome is specifically linked to leukemia, making it the correct answer.

**Final Answer:**
- The Philadelphia chromosome occurs in patients suffering from **leukemia**.

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