A hereditary disease which is seldom passed from father to son is

Options

A. (a) Autosomal linked disease
B. (b) X-chromosomal linked disease
C. (c) Y chromosomal linked disease
D. (d) None of the above

Answer

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks for a hereditary disease that is rarely passed from father to son. The term "seldom" indicates that this is an uncommon occurrence.

2. **Identifying Chromosomal Inheritance**: To answer this, we need to consider how hereditary diseases are passed on through chromosomes. There are two main types of chromosomes involved in inheritance: autosomes and sex chromosomes (X and Y).

3. **Analyzing Sex Chromosomes**:
- Males have one X and one Y chromosome (XY).
- Females have two X chromosomes (XX).
- When a son is conceived, he receives his Y chromosome from his father and one X chromosome from his mother.

4. **X-Linked Diseases**:
- X-linked diseases are those that are associated with genes located on the X chromosome.
- Since males inherit their Y chromosome from their fathers, they cannot inherit X-linked diseases from their fathers. Instead, they inherit the X chromosome from their mothers.

5. **Conclusion**: Since X-linked diseases are passed from mother to son (and not from father to son), these diseases are seldom passed from father to son. Therefore, the answer to the question is **X-linked hereditary disease**.

### Final Answer:
The hereditary disease which is seldom passed from father to son is **X-linked hereditary disease**.

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