Barr body is observed in

Options

A. (a) Basophils of male
B. (b) Neutrophils of female
C. (c) Basophils of female
D. (d) Eosinophils

Answer

### Step-by-Step Solution:

1. **Understanding Barr Body**:
- A Barr body is an inactivated X chromosome found in females. It is a form of sex chromatin that results from the process of X-inactivation, also known as lyonization.

2. **Location of Barr Bodies**:
- Barr bodies are primarily observed in the somatic cells of females. They are located in the nucleus, typically at the periphery.

3. **Sex Chromosome Composition**:
- In humans, females have two X chromosomes (XX), while males have one X and one Y chromosome (XY). To balance the dosage of X-linked genes, one of the X chromosomes in females is inactivated.

4. **Number of Barr Bodies**:
- In normal females, there is one Barr body present due to the inactivation of one X chromosome. In contrast, males do not have any Barr bodies since they only possess one X chromosome.

5. **Identifying the Correct Answer**:
- Given the options:
- A) Basophils of male - Incorrect (no Barr bodies in males)
- B) Neutrophils of female - Correct (Barr bodies present)
- C) Basophils of female - Correct (Barr bodies present)
- D) Eosinophils - Not specified, but irrelevant to the question.
- Therefore, the correct answers are B and C.

### Final Answer:
Barr bodies are observed in the neutrophils and basophils of females.

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