Epicanthus skin fold above the eyes and transverser plamer crase are typical symptoms of

Options

A. Cri-du-chat
B. Klinefelter's syndrome
C. Down 's syndrome
D. Truner 's syndrome

Answer

### Step-by-Step Solution:

1. **Identify the Symptoms**: The question mentions two specific symptoms: epicanthus skin fold above the eyes and transverse palmar crease.

2. **Understand Epicanthus Skin Fold**: The epicanthus skin fold is a fold of skin that covers the inner corner of the eye. It is often associated with certain genetic conditions.

3. **Understand Transverse Palmar Crease**: The transverse palmar crease is a single line that runs across the palm of the hand. This is also a characteristic feature seen in certain genetic disorders.

4. **Relate Symptoms to Genetic Disorders**: Both symptoms mentioned are commonly associated with Down syndrome, which is a genetic disorder caused by the trisomy of the 21st chromosome.

5. **Define Down Syndrome**: Down syndrome is characterized by a set of physical and intellectual disabilities. It is caused by the presence of an extra copy of chromosome 21, leading to various developmental issues.

6. **Conclude the Answer**: Based on the symptoms provided and their association with genetic disorders, the answer to the question is that these symptoms are typical of Down syndrome.

### Final Answer:
The typical symptoms of epicanthus skin fold above the eyes and transverse palmar crease are indicative of Down syndrome.

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