Which of the following sets of syndromes shows 47 chromosomes in their genetic make up

Options

A. Turner's syndrome, Edward's syndrome, Klinefelter's syndrome
B. Klinefelter' s syndorme, Turner's syndrome, Patau's syndrome
C. Down's syndrome , Patau's syndorme, Edward's syndrome
D. All the above.

Answer

To solve the question "Which of the following sets of syndromes shows 47 chromosomes in their genetic makeup?", we need to analyze each option provided and determine the chromosomal composition of the syndromes mentioned.

### Step-by-Step Solution:

1. **Understand Chromosomal Count in Syndromes**:
- Normal human cells have 46 chromosomes (23 pairs).
- Some syndromes are characterized by having an abnormal number of chromosomes.

2. **Evaluate Each Option**:
- **Option A**: Turner syndrome, Edwards syndrome, Kleene-Fletcher syndrome.
- Turner syndrome: 45 chromosomes (monosomy of the X chromosome).
- Edwards syndrome: 47 chromosomes (trisomy 18).
- Kleene-Fletcher syndrome: 47 chromosomes (trisomy 13).
- Conclusion: This option is incorrect due to Turner syndrome.

- **Option B**: Kleene-Fletcher syndrome, Turner syndrome, Tao's syndrome.
- Kleene-Fletcher syndrome: 47 chromosomes (trisomy 13).
- Turner syndrome: 45 chromosomes.
- Tao's syndrome: 47 chromosomes (trisomy 13).
- Conclusion: This option is incorrect due to Turner syndrome.

- **Option C**: Down's syndrome, Tao's syndrome, Edwards syndrome.
- Down's syndrome: 47 chromosomes (trisomy 21).
- Tao's syndrome: 47 chromosomes (trisomy 13).
- Edwards syndrome: 47 chromosomes (trisomy 18).
- Conclusion: This option is correct as all syndromes listed have 47 chromosomes.

- **Option D**: All of the above.
- Since not all syndromes in options A and B have 47 chromosomes, this option is incorrect.

3. **Final Answer**:
- The correct answer is **Option C**: Down's syndrome, Tao's syndrome, and Edwards syndrome, as all of these syndromes have 47 chromosomes in their genetic makeup.