In alpha thalasssemia the gene HBAI is located on chromosome

Options

A. 8
B. 22
C. 9
D. 16

Answer

To determine the chromosome on which the gene HBA1 is located in alpha thalassemia, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Alpha Thalassemia**: Alpha thalassemia is a blood disorder caused by the reduction or absence of alpha globin chains, which are essential components of hemoglobin.

2. **Identify the Gene in Question**: The gene HBA1 is responsible for producing the alpha globin chains.

3. **Locate the Gene Cluster**: The human alpha globin gene cluster, which includes the HBA1 gene, is known to be located on a specific chromosome.

4. **Research Chromosome Information**: It is established that the alpha globin gene cluster is located on chromosome 16. This includes the genes responsible for the production of alpha globin chains.

5. **Confirm the Answer**: Since HBA1 is part of the alpha globin gene cluster, we conclude that the gene HBA1 is located on chromosome 16.

### Final Answer:
The gene HBA1 in alpha thalassemia is located on chromosome **16**.

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