Curative technique involving repairing or replacement of defective genes is

Options

A. Gene therapy
B. Gene replacement therapy
C. Antisense therapy
D. Sense therapy

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks for a curative technique that involves the repairing or replacement of defective genes.

2. **Identifying the Options**: The options provided are:
- Option 1: Gene therapy
- Option 2: Gene replacement therapy
- Option 3: Antisense therapy
- Option 4: Sense therapy

3. **Analyzing Each Option**:
- **Gene therapy**: This is a technique that involves either repairing a defective gene or replacing it with a healthy one. It is specifically designed to treat genetic disorders by addressing the root cause, which is the defective gene.
- **Gene replacement therapy**: This specifically refers to replacing a defective gene with a normal one. While it is a part of gene therapy, it does not encompass the repairing aspect.
- **Antisense therapy**: This technique involves the use of synthetic oligonucleotides to bind to RNA molecules, thus inhibiting the expression of specific genes. It does not directly involve DNA repair or replacement.
- **Sense therapy**: Similar to antisense therapy, this involves RNA and does not pertain to the direct repair or replacement of genes.

4. **Conclusion**: Since gene therapy encompasses both the repairing and replacement of defective genes, it is the most appropriate answer to the question. Therefore, the correct answer is **Option 1: Gene therapy**.

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