Hypervariable repeats/minisatellite DNA sequences were discovered by

Options

A. Jeffreys et al
B. Sharp and Roberts
C. Persons et al
D. Sears and Sears.

Answer

To answer the question regarding who discovered hypervariable repeats or minisatellite DNA sequences, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Hypervariable Repeats**:
- Hypervariable repeats, also known as minisatellites, are DNA sequences that consist of short sequences of nucleotides that are repeated multiple times (typically 50 to 100 times). These sequences are important for genetic studies and forensic analysis due to their variability among individuals.

2. **Identifying the Options**:
- The question provides four options:
- Option 1: Jeffrey et al
- Option 2: Sharp and Roberts
- Option 3: Persons et al
- Option 4: Sears and Sears

3. **Analyzing Each Option**:
- **Option 1 (Jeffrey et al)**: Known for the discovery of hypervariable repeats/minisatellite DNA sequences.
- **Option 2 (Sharp and Roberts)**: Recognized for their work on RNA splicing, not related to minisatellites.
- **Option 3 (Persons et al)**: No significant contributions related to hypervariable repeats are noted.
- **Option 4 (Sears and Sears)**: They studied aneuploidy in wheat, which is unrelated to the discovery of minisatellites.

4. **Conclusion**:
- Based on the analysis, the correct answer is **Option 1: Jeffrey et al**. They were the researchers who discovered hypervariable repeats or minisatellite DNA sequences.

### Final Answer:
**Hypervariable repeats/minisatellite DNA sequences were discovered by Jeffrey et al.**

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