Split genes were discovered by

Options

A. Sharp and Roberts
B. Lyon
C. Ohno and Hanschka
D. de Robertis.

Answer

**Step-by-Step Solution:**

1. **Understanding Split Genes**: Split genes are genes that are not continuous but are instead made up of segments that are separated by non-coding regions. This means that the coding sequences (exons) are interrupted by non-coding sequences (introns).

2. **Historical Context**: The discovery of split genes significantly changed the understanding of gene structure. Prior to this discovery, it was commonly believed that genes were continuous sequences of DNA.

3. **Key Contributors**: The discovery of split genes is attributed to Richard J. Roberts and Philip A. Sharp. They conducted their research independently and published their findings in 1977.

4. **Identifying the Correct Answer**: The question asks who discovered split genes. Based on the information provided, the correct answer is Sharpe and Roberts, as they were the ones who identified that genes could be discontinuous.

5. **Conclusion**: Therefore, the correct answer to the question "Split genes were discovered by" is option A: Sharpe and Roberts.

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