Prefoetal globin is

Options

A. `zeta_(2)epsi_(2), alpha_(2)beta_(2), zeta_(2)gamma_(2)`
B. `zeta_(2)epsi_(2), zeta_(2)gamma_(2), alpha_(2)beta_(2)`
C. `zeta_(2)epsi_(2), zeta_(2)gamma_(2), alpha_(2)epsi_(2)`
D. `alpha_(2)beta_(2), alpha_(2)del_(2), alpha_(2)gamma_(2)`

Answer

To answer the question "Pre-fetal globin is," we will follow these steps:

### Step-by-Step Solution:

1. **Understanding Hemoglobin Stages**:
- In humans, hemoglobin types vary at different life stages: embryonic, fetal, and adult.
- The embryonic stage occurs during the early development of the embryo, while the fetal stage occurs later in pregnancy.

2. **Identifying the Types of Globins**:
- In the embryonic stage, three types of globins are produced:
- **Gover 1 (epsilon 2, zeta 2)**
- **Gover 2 (alpha 2, epsilon 2)**
- **Portland (Portland 1, which is gamma 2, zeta 2)**

3. **Fetal and Adult Hemoglobin**:
- As development progresses into the fetal stage, the predominant hemoglobin becomes fetal hemoglobin (HbF), which is composed of two alpha and two gamma chains (alpha 2, gamma 2).
- In adults, the main hemoglobin is HbA, which consists of two alpha and two beta chains (alpha 2, beta 2).

4. **Defining Pre-fetal Globin**:
- The term "pre-fetal" refers to the period before the fetal stage, specifically during the first four months of gestation.
- During this time, the globins produced are primarily from the embryonic stage.

5. **Eliminating Options**:
- Given the options, we need to identify which globin corresponds to the pre-fetal stage.
- The options include:
- Epsilon 2, zeta 2 (Gover 1)
- Alpha 2, epsilon 2 (Gover 2)
- Gamma 2, zeta 2 (Portland)
- The correct pre-fetal globin is **Epsilon 2, zeta 2**, which corresponds to the Gover 1 globin.

6. **Conclusion**:
- Therefore, the answer to the question "Pre-fetal globin is" is **Epsilon 2, zeta 2**.