Asymmetric karyotype is the one which has

Options

A. Fewer metacentric chromosomes
B. Large scale difference between large and small chromosomes
C. Both A and B.
D. Chromosomes with varied shape.

Answer

### Step-by-Step Solution:

1. **Understanding Karyotypes**: A karyotype is a complete set of chromosomes in an organism, arranged in pairs and organized by size, shape, and number.

2. **Defining Asymmetric Karyotype**: An asymmetric karyotype refers to a karyotype that exhibits significant differences in the size and shape of its chromosomes. This can include a variety of chromosome types, such as metacentric and telocentric chromosomes.

3. **Characteristics of Asymmetric Karyotype**:
- **Few Metacentric Chromosomes**: In an asymmetric karyotype, there are typically only a few chromosomes that are metacentric (chromosomes with the centromere located in the middle).
- **Large Scale Differences**: There is a noticeable size difference between the largest and smallest chromosomes in the karyotype. This means that the karyotype has a wide range of chromosome sizes.
- **Varied Shapes**: The chromosomes may also exhibit varied shapes, but this is not a defining characteristic of asymmetric karyotypes.

4. **Conclusion**: Based on the characteristics mentioned, an asymmetric karyotype is defined by having few metacentric chromosomes, a large scale difference between the largest and smallest chromosomes, and possibly varied shapes.

5. **Correct Answer**: Therefore, the correct answer to the question is that an asymmetric karyotype has:
- Few metacentric chromosomes
- Large scale differences between large and small chromosomes
- Both A and B are correct