An area is declared as "Hot Spot" when:

Options

A. It has 1500 or more endemic species and 75% its original habitat is lost
B. It has 1500 or move vertebrate species and 75 of its original habitat is lost
C. It has more than 2000 species of plants
D. Most of the species inhabiting the area is facing the risk of extinction.

Answer

### Step-by-Step Solution:

1. **Understanding Biodiversity Hotspots**: A biodiversity hotspot is defined as a biogeographic region that is both rich in endemic species and under significant threat from human activities.

2. **Criteria for Hotspot Designation**: For an area to be classified as a biodiversity hotspot, it must meet two specific criteria:
- **Criterion 1**: The area must contain at least **1,500 species of vascular plants** that are **endemic** to that region. Endemic species are those that are not found anywhere else in the world.
- **Criterion 2**: The area must have lost at least **70% to 75% of its original habitat**. This indicates a significant level of habitat destruction, which poses a threat to the species living there.

3. **Evaluating the Options**:
- The first option states that it has **1500 or more endemic species and 75% of its original habitat is lost**. This meets both criteria.
- The second option mentions **1500 or more vertebrate species and 75% of its original habitat is lost**, which does not satisfy the requirement for endemic vascular plants.
- The third option states **more than 2000 species of plants or most of the species inhabiting the area is facing the lack of extinction**, which does not align with the specific criteria for hotspot designation.

4. **Conclusion**: Based on the criteria outlined, the correct answer is that an area is declared as a "Hot Spot" when it has **1500 or more endemic species and 75% of its original habitat is lost**.