Choose the wrong statement regarding AIDS

Options

A. It is an immunodeficiency disease
B. It is caused by retrovirus HIV
C. HIV Selectively infects and kills B-lymophocytes
D. Genome RNA replicates via DNA intermediate

Answer

To answer the question "Choose the wrong statement regarding AIDS," let's analyze each of the provided statements step by step.

### Step 1: Understanding AIDS
AIDS stands for Acquired Immunodeficiency Syndrome. It is a condition that results from the infection of the Human Immunodeficiency Virus (HIV), which severely weakens the immune system.

### Step 2: Analyzing the Statements
1. **Statement 1: It is an immunodeficiency disease.**
- This statement is **correct**. AIDS is indeed an immunodeficiency disease as it compromises the immune system.

2. **Statement 2: It is caused by retrovirus HIV.**
- This statement is also **correct**. HIV is classified as a retrovirus, which means it has RNA as its genetic material and uses reverse transcriptase to convert RNA into DNA.

3. **Statement 3: HIV selectively infects and kills B lymphocytes.**
- This statement is **incorrect**. HIV primarily targets T helper cells (CD4 cells), not B lymphocytes. Therefore, this is the wrong statement regarding AIDS.

4. **Statement 4: Genome RNA replicates via DNA intermediate.**
- This statement is **correct**. The replication process of HIV involves converting its RNA genome into DNA, which is then integrated into the host's genome.

### Conclusion
The wrong statement regarding AIDS is: **"HIV selectively infects and kills B lymphocytes."**

### Final Answer
The wrong statement is: **HIV selectively infects and kills B lymphocytes.**

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