Read the statement and find the correct ones
1. IgE antibodies are produced in an allergic reaction
2. B-lymphocytes mediate cell mediated immunity
3. The yellow fluid colostrum has abundant IgE antibodies
4. spleen is a secondary lymphoid organ

Options

A. 1 only
B. 1 and 2
C. 2 and 3
D. 1 and 4

Answer

To determine which statements are correct, let's evaluate each one step by step.

### Step 1: Evaluate Statement 1
**Statement:** IgE antibodies are produced in an allergic reaction.
**Evaluation:** This statement is correct. IgE antibodies are indeed produced during allergic reactions. They bind to mast cells, which then release histamine, leading to allergy symptoms.

### Step 2: Evaluate Statement 2
**Statement:** B-lymphocytes mediate cell-mediated immunity.
**Evaluation:** This statement is incorrect. B-lymphocytes are primarily responsible for humoral immunity, which involves the production of antibodies. Cell-mediated immunity is primarily mediated by T-lymphocytes.

### Step 3: Evaluate Statement 3
**Statement:** The yellow fluid colostrum has abundant IgE antibodies.
**Evaluation:** This statement is incorrect. Colostrum, the first form of milk produced after giving birth, is rich in IgG antibodies, not IgE. It contains lower amounts of IgA and IgM.

### Step 4: Evaluate Statement 4
**Statement:** Spleen is a secondary lymphoid organ.
**Evaluation:** This statement is correct. The spleen is classified as a secondary lymphoid organ, where immune responses can be initiated, and it contains T and B lymphocytes.

### Conclusion
The correct statements are:
1. IgE antibodies are produced in an allergic reaction.
4. Spleen is a secondary lymphoid organ.

### Final Answer
The correct statements are 1 and 4.

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