Okazaki fragments give rise to
(a) Master strand
(b) Sense strand
(c) Lagging strand
(d) Leading strand

Options

A. Master strand
B. Sense strand
C. Lagging strand
D. Leading strand

Answer

To solve the question regarding Okazaki fragments, we need to understand their role in DNA replication. Here’s a step-by-step breakdown of the solution:

### Step 1: Understand what Okazaki fragments are
Okazaki fragments are short sequences of DNA that are synthesized during DNA replication. They are formed on the lagging strand, which is synthesized discontinuously.

**Hint:** Remember that Okazaki fragments are associated with the lagging strand, not the leading strand.

### Step 2: Identify the context of DNA replication
During DNA replication, the two strands of the DNA helix separate. DNA polymerase synthesizes new DNA strands in the 5' to 3' direction. The leading strand is synthesized continuously, while the lagging strand is synthesized in short segments (Okazaki fragments) because it runs in the opposite direction.

**Hint:** Focus on the direction of synthesis and the differences between leading and lagging strands.

### Step 3: Analyze the options given in the question
- (a) Master strand: This term is not commonly used in DNA replication.
- (b) Sense strand: This refers to the strand of DNA that has the same sequence as the mRNA (except for thymine vs. uracil) but is not directly related to Okazaki fragments.
- (c) Lagging strand: This is the correct answer, as Okazaki fragments are formed on the lagging strand during replication.
- (d) Leading strand: This is synthesized continuously and does not involve Okazaki fragments.

**Hint:** Eliminate options that do not relate to the process of DNA replication involving Okazaki fragments.

### Step 4: Conclude the correct answer
Given that Okazaki fragments are specifically formed on the lagging strand during DNA replication, the correct answer is (c) Lagging strand.

**Final Answer:** (c) Lagging strand