Which event is not associated with ovulation in human female .

Options

A. Decrease in estradiol
B. Full development of Graafian follicle
C. Release of secondary oocyte
D. LH surge.

Answer

To determine which event is not associated with ovulation in human females, we can analyze each option provided in the question.

### Step-by-Step Solution:

1. **Understanding Ovulation**: Ovulation is the process during the menstrual cycle when a mature ovarian follicle releases a secondary oocyte. It is a crucial event in female reproduction.

2. **Analyzing the Options**:
- **Option A: Decrease in Estradiol**: Estradiol (also known as estrogen) is a hormone that peaks before ovulation. A decrease in estradiol is not directly associated with the ovulation event itself. Instead, estradiol levels typically rise leading up to ovulation and then may decrease after ovulation occurs.

- **Option B: Full Development of Graafian Follicle**: The Graafian follicle is the mature follicle that releases the oocyte during ovulation. This event is directly associated with ovulation.

- **Option C: Release of Secondary Oocyte**: This is the primary event of ovulation, where the secondary oocyte is released from the ovary.

- **Option D: Elixir**: This option seems to be a typographical error or irrelevant term in the context of ovulation and does not correspond to any known biological event associated with ovulation.

3. **Conclusion**: Among the options, the event that is not associated with ovulation is **Option A: Decrease in Estradiol**. This is because a decrease in estradiol does not occur as a direct event of ovulation; rather, estradiol levels are typically higher leading up to ovulation.

### Final Answer:
**Option A: Decrease in Estradiol**

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