Which of the following layers is acellular in antral follicle

Options

A. Granulosa
B. Theca interna
C. Stroma
D. Zona pellucida.

Answer

To determine which layer is acellular in the antral follicle, we can analyze the options provided:

1. **Granulosa**: This layer is composed of granulosa cells that surround the oocyte. It is not acellular as it consists of living cells.

2. **Theca interna**: This layer is made up of theca cells that play a role in hormone production. Like the granulosa, it is not acellular.

3. **Stroma**: The stroma is the connective tissue that supports the follicle. It contains cells and is therefore not acellular.

4. **Zona pellucida**: This is a glycoprotein layer that surrounds the oocyte. It is acellular, meaning it does not contain any living cells.

Based on this analysis, the correct answer is:

**Option D: Zona pellucida**

### Step-by-Step Solution:
1. **Identify the layers of the antral follicle**: Understand the different layers that make up the antral follicle, which include granulosa, theca interna, stroma, and zona pellucida.

2. **Analyze each layer**: Determine whether each layer is composed of cells or is acellular.
- Granulosa: Composed of granulosa cells (not acellular).
- Theca interna: Composed of theca cells (not acellular).
- Stroma: Contains connective tissue cells (not acellular).
- Zona pellucida: A glycoprotein layer surrounding the oocyte (acellular).

3. **Select the acellular layer**: From the analysis, identify that the zona pellucida is the only layer that is acellular.

4. **Conclude the answer**: Confirm that the answer to the question is option D, zona pellucida.