Name the chemicals responsible for minimata disease and itai-itai disease, respectively.

Explanation

**Step-by-Step Solution:**

1. **Identify the diseases**: The two diseases mentioned in the question are Minamata disease and Itai-Itai disease.

2. **Research Minamata disease**: Minamata disease is a neurological disorder that primarily affects the brain and nervous system.

3. **Determine the chemical for Minamata disease**: The chemical responsible for Minamata disease is mercury. Mercury poisoning leads to various symptoms, including muscle weakness, loss of peripheral vision, and damage to hearing and speech.

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