Assertion: Exocrine gland are without ducts secrete hormones passing directly to blood.
Reason: Endocrine glands are with duct.

Options

A. If both Assertion and Reason are true and Reason is the correct explanation of Assertion.
B. If both Assertion and Reason are true, but Reason is not the correct explanation of Assertion.
C. If Assertion is true, but Reason is false.
D. Both Assertion and Reason are false.

Answer

### Step-by-Step Solution:

1. **Understanding the Assertion**: The assertion states that "Exocrine glands are without ducts and secrete hormones passing directly to blood."
- **Analysis**: This is incorrect because exocrine glands do not secrete hormones; they secrete substances (like enzymes, sweat, etc.) through ducts to specific sites.

2. **Understanding the Reason**: The reason states that "Endocrine glands are with duct."
- **Analysis**: This is also incorrect because endocrine glands do not have ducts. Instead, they secrete hormones directly into the bloodstream.

3. **Conclusion**: Since both the assertion and the reason are incorrect, we can conclude that the answer is that both statements are false.

4. **Final Answer**: The correct answer is option number 4, which states that both the assertion and the reason are false.