An unaffected woman whose father had haemophilia marries a man who has haemophilia. What is the chance their sons will be haemophiliacs? What is the chance that their daughters will be haemophiliacs?

Explanation

To solve the problem of determining the chances of the sons and daughters of an unaffected woman (whose father had hemophilia) and a man with hemophilia being affected by the disorder, we can follow these steps:

### Step 1: Understand the Genetics of Hemophilia
Hemophilia is an X-linked recessive disorder. This means that the gene responsible for hemophilia is located on the X chromosome. Males have one X and one Y chromosome (XY), while females have two X chromosomes (XX).

### Step 2: Determine the Genotype of the Woman
The woman is unaffected, but her father had hemophilia. Since her father has hemophilia, he must have the genotype X^hY (where X^h represents the X chromosome with the hemophilia allele). The mother of the woman must have been normal (XX). Therefore, the woman must have inherited one normal X chromosome from her mother and one affected X chromosome from her father. Thus, her genotype is X^hX.

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