What is the effect of denaturation on the structure of proteins?

Explanation

During denaturation, `2^@` and `3^@` structures of proteins are destroyed but `1^@` structure remains aintact: As a result of denaturation, the globular proteins which are soluble in water are converted into insoluble fibrous proteins and their biological acitivity in lost. For example, boiled egg which contains coagulated proteins cannot be hatched.