Aspiriin can be prepared by the reaction of:-

Options

A. Sallicylic acid with methanol in presence of `H_(2)SO_(4)`
B. Salicyldehyde with acetic anhydride in presence of `H_(2)SO_(4)`
C. Salicylic acid with acetic anhydride in presence of `H_(2)SO_(4)`
D. Cinnamic acid with acetic anhydride in presence of `H_(2)SO_(4)`

Answer

To prepare aspirin, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Reactants**: Aspirin, also known as acetylsalicylic acid, can be synthesized from salicylic acid and acetic anhydride. Salicylic acid has the structure with a hydroxyl group (-OH) and a carboxylic acid group (-COOH).

2. **Write the Reaction Equation**: The reaction can be represented as:
\[ \text{Salicylic Acid (C}_7\text{H}_6\text{O}_3\text{)} + \text{Acetic Anhydride (C}_4\text{H}_6\text{O}_3\text{)} \rightarrow \text{Aspirin (C}_9\text{H}_8\text{O}_4\text{)} + \text{Acetic Acid (C}_2\text{H}_4\text{O}_2\text{)} \]

3. **Mechanism of the Reaction**:
- The hydroxyl group of salicylic acid attacks the carbonyl carbon of acetic anhydride, leading to the formation of an intermediate.
- This intermediate undergoes a rearrangement where the acetic acid is released, and the acetyl group is transferred to the salicylic acid, resulting in the formation of aspirin.

4. **Final Product**: The final product of this reaction is acetylsalicylic acid (aspirin) and acetic acid.

5. **Conclusion**: Therefore, the correct answer to the question "Aspirin can be prepared by the reaction of:" is salicylic acid and acetic anhydride.

### Final Answer:
Aspirin can be prepared by the reaction of **salicylic acid and acetic anhydride**.

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