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Ester gives nucleophilic addition reacti...

Ester gives nucleophilic addition reaction followed by elimination reaction with carbon nucleopile. When carbon nucleophile is of an ester then the reaction is known as Claisen condensation reaction. This reaction is also carried out between ester and a ketone. A suC Cessful Claisen condensation requires an ester with two `alpha-` hydrogens and an equivalent amount of base rather than a catalytic amount of base. Consider the given reaction
`CH_(3)-COOC_(2)H_(5)underset(C_(2)H_(5)OH)overset(C_(2)H_(5)ONa)rarr"enolate ion"underset("Claisen condensation")overset("ether(X)")rarr` Product
For the above reaction the most reactive ester is :

A

`C_(6)H_(5)COOC_(2)H_(5)`

B

`C_(2)H_(5)O-overset(O)overset(||)C-overset(O)overset(||)C-OC_(2)H_(5)`

C

`HCOOC_(2)H_(5)`

D

`C_(2)H_(5)O-overset(O)overset(||)C-OC_(2)H_(5)`

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The correct Answer is:
B
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Ester gives nucleophilic addition reaction followed by elimination reaction with carbon nucleopile. When carbon nucleophile is of an ester then the reaction is known as Claisen condensation reaction. This reaction is also carried out between ester and a ketone. A suC Cessful Claisen condensation requires an ester with two alpha- hydrogens and an equivalent amount of base rather than a catalytic amount of base. Intramolecular Claisen condensation given diester is known as :

Claisen Condensation.

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Which of the following does not give claisen condensation reaction :

ALLEN-ALKENE, ALKANE & ALKYNE -EXCERSISE-3
  1. Hell-Volhard-Zelinsky reaction involves the replacement of an ...........

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  2. Carboxylic acids may be prepared by the reaction of Grigrand reagents ...

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  3. Statement-I: Unlike the gtC=O group of aldehydes and ketones, the C=O ...

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  4. Statement-I: CH(3)COCH(2)COOC(2)H(5) will give iodoform test. Becau...

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  5. Statement-1: Acetic acid does not undergo haloform test. and State...

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  6. Statement-I: Benzoic acid on nitration will give m- nitro benzoic ac...

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  7. Statement-I: Acyl halide are more reactive than acid substance amide t...

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  8. Amides undergo hydrolysis to yield carboxylic acid plus amine on heati...

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  9. Amides undergo hydrolysis to yield carboxylic acid plus amine on heati...

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  10. Acid halides are more reactive than acid amides towards the hydrolysis...

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  11. When is treated with two equivalent of methyl magnesium iodide a...

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  12. Ester gives nucleophilic addition reaction followed by elimination rea...

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  13. Ester gives nucleophilic addition reaction followed by elimination rea...

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  14. In the given reaction : C(2)H(5)O-overset(O)overset(||)C-(CH(2))(3)-CH...

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  15. In the given reaction [X] is :

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  16. The reactivity of acid derivatives in general follows the order : ...

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  17. The reactivity of acid derivatives in general follows the order : ...

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  18. The reactivity of acid derivatives in general follows the order : ...

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  19. The reactivity of acid derivatives in general follows the order : ...

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  20. The reactivity of acid derivatives in general follows the order : ...

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