Receptors of opioids are present in

Options

A. CNS
B. GIT
C. Both (1) and (2)
D. Spleen

Answer

**Step-by-Step Solution:**

1. **Understanding Opioid Receptors**: Opioid receptors are specific proteins found in the body that bind to opioid substances. These receptors are crucial for mediating the effects of opioids, which include pain relief and euphoria.

2. **Sources of Opioids**: Opioids are derived from the opium poppy plant, specifically from the species *Papaver somniferum*. The unripe capsules of this plant are harvested to produce various opioid drugs.

3. **Examples of Opioids**: Common examples of opioids include Heroin and Morphine. These substances interact with opioid receptors in the body.

4. **Location of Opioid Receptors**: Opioid receptors are primarily located in two main areas:
- The **Central Nervous System (CNS)**: This includes the brain and spinal cord, where they play a significant role in pain modulation and the effects of opioids.
- The **Gastrointestinal Tract**: Opioid receptors are also present here, influencing gut motility and other digestive functions.

5. **Elimination of Incorrect Options**:
- The spleen is mentioned as a secondary lymphoid organ and a reservoir for red blood cells, but it does not contain opioid receptors. Therefore, it can be ruled out as a location for these receptors.

6. **Conclusion**: Based on the information, the correct answer to the question is that opioid receptors are present in the **Central Nervous System** and the **Gastrointestinal Tract**.

**Final Answer**: Opioid receptors are present in the Central Nervous System and the Gastrointestinal Tract.

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