Below are some statements related to life cycle of plasmodium. Which of the following is correct ?

Options

A. Gametocyte stage infects human body
B. it multiplies by sexual method of reproduction in human liver
C. human RBC are ruptured and releases a toxin hemozoin
D. development of gametocyte possible only in female culex mosquito

Answer

To determine which statement about the life cycle of Plasmodium is correct, we will analyze each of the provided statements step by step.

### Step-by-Step Solution:

1. **Understanding Plasmodium**:
- Plasmodium is a protozoan parasite that causes malaria in humans. It is transmitted through the bite of infected female Anopheles mosquitoes.

2. **Identifying the Stages of Plasmodium**:
- The life cycle of Plasmodium includes several stages:
- **Sporozoite Stage**: This is the stage that infects humans when the mosquito bites.
- **Asexual Reproduction**: Occurs in the liver and red blood cells (RBCs) of the human host.
- **Gametocyte Stage**: This stage is involved in sexual reproduction and occurs in the mosquito.

3. **Analyzing the Statements**:
- **Statement 1**: "Gametocyte stage infects human body."
- This statement is incorrect. The sporozoite stage infects the human body, not the gametocyte stage.

- **Statement 2**: "It multiplies by sexual method of reproduction."
- This statement is also incorrect. Plasmodium multiplies asexually in the human host and sexually in the mosquito.

- **Statement 3**: "Human RBC are ruptured and releases a toxin hemozoin."
- This statement is correct. When Plasmodium infects RBCs, they rupture, releasing hemozoin, which contributes to the symptoms of malaria.

- **Statement 4**: "Development of gametocyte possible only in female Culex mosquito."
- This statement is incorrect. The development of gametocytes occurs in female Anopheles mosquitoes, not Culex mosquitoes.

4. **Conclusion**:
- The only correct statement among the options provided is Statement 3: "Human RBC are ruptured and releases a toxin hemozoin."

### Final Answer:
The correct statement regarding the life cycle of Plasmodium is: **"Human RBC are ruptured and releases a toxin hemozoin."**

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