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Which dieases is sex linked recessive di...

Which dieases is sex linked recessive disease ?

A

Haemophilia

B

Sickle cell anaemia

C

Phenylketonuria

D

Thalassemia

Text Solution

AI Generated Solution

The correct Answer is:
**Step-by-Step Solution:** 1. **Understanding Sex-Linked Recessive Diseases:** - Sex-linked diseases are caused by mutations in sex chromosomes. In humans, females have two X chromosomes (XX), while males have one X and one Y chromosome (XY). - Recessive diseases require that an individual must have two copies of the recessive allele (homozygous recessive) for the disease to manifest. If an individual has one dominant allele, they will not show symptoms but can be a carrier. 2. **Identifying the Diseases:** - The question lists four diseases: hemophilia, sickle-cell anemia, phenylketonuria, and thalassemia. - We need to determine which of these is a sex-linked recessive disease. 3. **Analyzing Hemophilia:** - Hemophilia is characterized by the inability of blood to clot properly, leading to prolonged bleeding. - It is known to be a sex-linked recessive disease because the mutation occurs on the X chromosome. Males, having only one X chromosome, are more frequently affected. Females can be carriers if they have one affected X chromosome. 4. **Analyzing Other Diseases:** - **Sickle-cell anemia**: This is an autosomal recessive disease, not sex-linked. - **Phenylketonuria (PKU)**: This is also an autosomal recessive disease. - **Thalassemia**: This is another autosomal recessive disease. 5. **Conclusion:** - Among the diseases listed, hemophilia is the only sex-linked recessive disease. **Final Answer: Hemophilia is a sex-linked recessive disease.** ---
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