Eli Lilly an American company is famous for

Options

A. producing vitamin -A enriched rice
B. Producing pest resistance plants, by RNA interferance
C. Producing GH (Grwoth hormone) synthesised by recombinant DNA technology
D. Producing two DNA sequences corresponding to A and B chain of human insulin and introduced them in the plasmids of E.coli to produce insulin chain.

Answer

**Step-by-Step Solution:**

1. **Identify the Company:** Eli Lilly is an American pharmaceutical company headquartered in Indianapolis.

2. **Understand Its Contributions:** The company is known for its advancements in biotechnology and pharmaceuticals, particularly in the field of insulin production.

3. **Focus on Insulin Production:** Eli Lilly is particularly famous for producing Humulin, which is a form of human insulin. This insulin is used to treat diabetes, specifically insulin-dependent diabetes.

4. **Recombinant DNA Technology:** The production of Humulin involves recombinant DNA technology, where two DNA sequences corresponding to the A and B chains of human insulin are synthesized.

5. **Transformation into E. coli:** These DNA sequences are then introduced into plasmids of E. coli bacteria. The bacteria then produce the insulin chains, which can be harvested and used for medical purposes.

6. **Conclusion:** Therefore, the correct answer to the question regarding what Eli Lilly is famous for is: "producing two DNA sequences corresponding to A and B chain of human insulin and introducing them in the plasmid E. coli to produce insulin chain."

**Final Answer:** Eli Lilly is famous for producing two DNA sequences corresponding to the A and B chain of human insulin and introducing them into the plasmid E. coli to produce insulin chains.

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