nu body of nucleosome consists of

Options

A. `H_(1)and H_(2)A`
B. `H_(2)Aand H_(2)B`
C. `H_(3)and H_(4)`
D. Both 2 and 3

Answer

To answer the question "What does the nucleosome consist of?", we can break it down into the following steps:

### Step-by-Step Solution:

1. **Understanding Nucleosome**:
- A nucleosome is the fundamental unit of chromatin, which is the material that makes up chromosomes. It consists of DNA wrapped around histone proteins.

2. **Components of Nucleosome**:
- The nucleosome consists of a core of histone proteins around which DNA is wrapped. The core is made up of an octamer of histone proteins.

3. **Histone Proteins**:
- The histone proteins that make up the nucleosome include:
- **H2A**
- **H2B**
- **H3**
- **H4**
- These four types of histone proteins form the core of the nucleosome.

4. **Role of H1 Histone**:
- There is also a fifth type of histone protein known as **H1**, which is associated with the linker DNA between nucleosomes but is not part of the core octamer.

5. **Conclusion**:
- Therefore, the nucleosome primarily consists of the histone proteins H2A, H2B, H3, and H4, which form the core, while H1 is associated with the structure but not part of the core.

### Final Answer:
The nucleosome consists of histone proteins H2A, H2B, H3, and H4.

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