DNA replication in lagging strand of most of the eukaryotic organisms is :-

Options

A. Conservative and continous
B. Semi-conservative but discontinous
C. Consenrvative and semi-discontinous
D. Semi-conservative but continous

Answer

### Step-by-Step Solution:

1. **Understanding DNA Replication**: DNA replication is the process by which a cell duplicates its DNA before cell division. It involves unwinding the double helix and synthesizing new strands complementary to the original strands.

2. **Identifying Leading and Lagging Strands**: During replication, one strand (the leading strand) is synthesized continuously in the same direction as the replication fork, while the other strand (the lagging strand) is synthesized in the opposite direction in short segments.

3. **Characteristics of the Lagging Strand**: The lagging strand is synthesized in short fragments known as Okazaki fragments. These fragments are approximately 100 to 150 nucleotides long and are initiated by RNA or DNA primers.

4. **Discontinuous Synthesis**: Because the lagging strand is synthesized in short fragments, it is considered discontinuous. This means that the synthesis does not occur in a continuous manner but rather in segments that are later joined together.

5. **Semi-Conservative Nature**: The term "semi-conservative" refers to the fact that each new DNA molecule consists of one original (parental) strand and one newly synthesized strand. This applies to both the leading and lagging strands.

6. **Evaluating the Options**: The question provides several options regarding the nature of DNA replication in the lagging strand:
- Conservative and continuous
- Semi-conservative but discontinuous
- Conservative and semi-discontinuous
- Semi-conservative but continuous

Based on the characteristics discussed, the correct answer is **semi-conservative but discontinuous**.

### Final Answer:
**DNA replication in the lagging strand of most eukaryotic organisms is semi-conservative but discontinuous.**

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