Which of the following is a false statements ?

Options

A. DNA is chemically less reactive, as compared to RNA
B. RNA mutate at a faster rate, as compared to DNA
C. Guanyl transferase enzyme helps in capping process during splicing of hn-RNA
D. Sweetness index of saccharine is `10,000`

Answer

To determine which statement is false among the provided options, we will analyze each statement one by one.

### Step-by-Step Solution:

1. **Evaluate Option A**:
- **Statement**: DNA is chemically less reactive as compared to RNA.
- **Analysis**: This statement is true. DNA is more stable and less reactive than RNA due to its double-stranded structure and the presence of deoxyribose sugar, which lacks a hydroxyl group at the 2' carbon that is present in ribose (the sugar in RNA).

2. **Evaluate Option B**:
- **Statement**: RNA mutates at a faster rate as compared to DNA.
- **Analysis**: This statement is also true. RNA viruses, for example, have higher mutation rates due to the lack of proofreading mechanisms during replication compared to DNA. Therefore, RNA can accumulate mutations more rapidly.

3. **Evaluate Option C**:
- **Statement**: Guanyl transferase enzyme helps in the capping process during splicing of hnRNA.
- **Analysis**: This statement is true. Guanyl transferase is indeed involved in the capping of heterogeneous nuclear RNA (hnRNA) after transcription, which is an essential step in RNA processing.

4. **Evaluate Option D**:
- **Statement**: Sweetness index of saccharin is 10,000.
- **Analysis**: This statement is false. The sweetness of saccharin is approximately 300 to 400 times sweeter than sucrose, not 10,000 times. Therefore, this statement is incorrect.

### Conclusion:
The false statement among the options provided is **Option D**: "Sweetness index of saccharin is 10,000."

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