Which of the following undergoes change in mutation :-

Options

A. Chromosome
B. Structure of gene
C. Sequence of gene
D. Any of the above

Answer

To solve the question "Which of the following undergoes change in mutation?", we will analyze each option provided:

1. **Chromosome**:
- Mutations can lead to changes in the number of chromosomes, such as in conditions like Down syndrome, where there is an extra chromosome 21. This indicates that mutations can indeed affect chromosomes.

2. **Structure of Gene**:
- Mutations can also alter the structure of a gene. This can occur through processes such as deletion (removing a part of the gene), inversion (reversing a segment of the gene), or translocation (moving a segment of the gene to a different location). Therefore, mutations can change the structure of genes.

3. **Sequence of Gene**:
- The sequence of a gene can change due to mutations as well. For example, if nucleotides are added (insertion) or removed (deletion), the sequence of the gene is altered. This is a direct impact of mutation on the gene's sequence.

4. **Any of the Above**:
- Since mutations can affect chromosomes, the structure of genes, and the sequence of genes, the correct answer must be that all of these options can undergo change due to mutations.

**Final Answer**: The correct option is **D. Any of the above**.