In density gradient centrifugation, the bulk DNA forms____ while satelite DNA forms____

Options

A. Major peak, Minor peak
B. Minor peak, Major peak
C. Major peak, Major peak
D. Mainor peak, minor peak

Answer

**Step-by-Step Solution:**

1. **Understanding Density Gradient Centrifugation**:
- Density gradient centrifugation is a technique used to separate different components of a mixture based on their density. When a sample is spun in a centrifuge, denser particles move outward while less dense particles remain closer to the center.

2. **Identifying the Components**:
- In the context of DNA, we have two types: bulk DNA and satellite DNA. Bulk DNA refers to the majority of the genomic DNA, while satellite DNA consists of tandem repeats of non-coding sequences.

3. **Behavior of Bulk DNA**:
- Bulk DNA is denser compared to satellite DNA. Therefore, during centrifugation, it will migrate outward to form a distinct layer.

4. **Behavior of Satellite DNA**:
- Satellite DNA, being less dense than bulk DNA, will not travel as far outward. Instead, it will settle closer to the center of the centrifuge tube.

5. **Formation of Peaks**:
- As a result of this separation, bulk DNA forms a major peak due to its higher density, while satellite DNA forms a minor peak, indicating its lower density.

6. **Conclusion**:
- Thus, in density gradient centrifugation, the bulk DNA forms a **major peak**, and the satellite DNA forms a **minor peak**.

**Final Answer**:
- The bulk DNA forms a major peak, while the satellite DNA forms a minor peak.

---