Which antibiotic inhibits interaction between t RNA and m RNA during bacterial synthesis

Options

A. Etythromycin
B. Neomycin
C. Streptomycin
D. Tetracycline

Answer

**Step-by-Step Solution:**

1. **Understanding the Question:**
- The question asks which antibiotic inhibits the interaction between tRNA and mRNA during bacterial protein synthesis.

2. **Identifying Key Components:**
- tRNA (transfer RNA) is responsible for carrying amino acids to the ribosome, where mRNA (messenger RNA) is translated into a polypeptide chain.
- The interaction between tRNA and mRNA is crucial for the correct addition of amino acids during protein synthesis.

3. **Considering the Options:**
- The question likely provides multiple-choice options, including various antibiotics. We need to identify which one specifically affects the tRNA-mRNA interaction.

4. **Analyzing Antibiotics:**
- **Tetracycline:** This antibiotic is known to inhibit the attachment of tRNA to the mRNA-ribosome complex, thus preventing the addition of amino acids to the growing polypeptide chain.
- **Streptomycin:** This antibiotic interferes with the initial stages of protein synthesis by altering the shape of the 30S ribosomal subunit but does not directly inhibit tRNA-mRNA interaction.
- **Erythromycin:** This antibiotic interacts with the 50S ribosomal subunit and affects protein synthesis but does not specifically target the tRNA-mRNA interaction.

5. **Conclusion:**
- Based on the analysis, the antibiotic that inhibits the interaction between tRNA and mRNA during bacterial protein synthesis is **Tetracycline**.

6. **Final Answer:**
- The correct answer is **Tetracycline**.

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