Assertion :- The replication of DNA and cell division cycle should be highly coordinated.
Reason : A failure in cell division after DNA replication results into chromosomal anomaly.

Options

A. If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion.
B. If both Assertion & Reason are trur but Reason is not a correct explanation of the Assertion.
C. If Assertion is True but the Reason is Flase.
D. If both Assertion & Reason are false.

Answer

**Step-by-Step Solution:**

1. **Understanding the Assertion**: The assertion states that the replication of DNA and the cell division cycle should be highly coordinated. This means that the processes of DNA replication and cell division must occur in a synchronized manner to ensure proper cell function and genetic stability.

2. **Identifying the Phases**: DNA replication occurs during the S phase (synthesis phase) of the cell cycle. This phase is part of the interphase, which is the period when the cell prepares for division. Following the S phase, the cell enters the M phase (mitotic phase), where the actual division of the cell occurs.

3. **Explaining the Coordination**: The coordination between DNA replication and cell division is crucial because if DNA is replicated but the cell does not divide properly, it can lead to cells with abnormal numbers of chromosomes. This coordination ensures that each daughter cell receives the correct amount of genetic material.

4. **Understanding the Reason**: The reason provided states that a failure in cell division after DNA replication can result in chromosomal anomalies. For instance, if karyokinesis (the division of the nucleus) occurs but cytokinesis (the division of the cytoplasm) does not, the resulting cell will have double the number of chromosomes (4N instead of the normal 2N).

5. **Conclusion**: Both the assertion and the reason are true. The assertion correctly identifies the need for coordination between DNA replication and cell division, and the reason accurately explains the consequences of a failure in this coordination.

6. **Final Answer**: Therefore, the correct answer is that both the assertion and reason are true, and the reason correctly explains the assertion.

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