Assertion :- RNA polymerase associates with `sigma`-factor and `rho`-factor to terminate & initiate the transcription respectively.
Reason: Association with these factors will not alter the specificity
of the RNA polymerase.

Options

A. If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion.
B. If both Assertion & Reason are trur but Reason is not a correct explanation of the Assertion.
C. If Assertion is True but the Reason is Flase.
D. If both Assertion & Reason are false.

Answer

### Step-by-Step Solution:

1. **Understanding the Assertion**:
- The assertion states that RNA polymerase associates with sigma factor and rho factor to terminate and initiate transcription respectively.
- **Correction**: The sigma factor is involved in the initiation of transcription, while the rho factor is involved in termination. Therefore, the assertion is incorrect.

2. **Understanding the Reason**:
- The reason states that the association with these factors will not alter the specificity of RNA polymerase.
- **Correction**: The binding of sigma factor does indeed increase the specificity of RNA polymerase by guiding it to specific promoters. Therefore, this statement is also incorrect.

3. **Evaluating the Options**:
- Based on the analysis, both the assertion and the reason are false.
- The options provided are:
- A) Both assertion and reason are true, and reason is the correct explanation of the assertion.
- B) Both assertion and reason are true, but reason is not the correct explanation of the assertion.
- C) Assertion is true, but reason is false.
- D) Both assertion and reason are false.
- Since both the assertion and reason are false, the correct answer is option D.

### Final Answer:
Both assertion and reason are false (Option D).