Assertion :- ESTs are the sequences in DNA that exprossed as RNA.
Reason : Sequence Annotation is the blind approach of sequencing entire codeing sequence of genome.

Options

A. If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion.
B. If both Assertion & Reason are true but Reason is not a correct explanation of the Assertion.
C. If Assertion is True but the Reason is False.
D. If both Assertion & Reason are false.

Answer

### Step-by-Step Solution:

1. **Understand the Assertion**:
- The assertion states that "ESTs are the sequences in DNA that are expressed as RNA."
- This is true because ESTs (Expressed Sequence Tags) are derived from the parts of the genome that are transcribed into mRNA, which are the coding sequences.

2. **Understand the Reason**:
- The reason states that "Sequence Annotation is the blind approach of sequencing the entire coding sequence of the genome."
- This statement is false. Sequence annotation involves identifying both coding and non-coding regions of the genome, not just coding sequences.

3. **Evaluate the Relationship**:
- Since the assertion is true and the reason is false, the reason does not provide a correct explanation for the assertion.

4. **Select the Correct Option**:
- Based on the evaluation, the correct option is C: "Assertion is true but the reason is false."

### Final Answer:
The correct answer is Option C: Assertion is true but the reason is false.

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