Assertion :- For sequencing, the total DNA from a cell is isolated and converted into random fragments.
Reason : DNA is a long polymer & there are technical limitations in sequencing very long pieces of DNA.

Options

A. If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion.
B. If both Assertion & Reason are trur but Reason is not a correct explanation of the Assertion.
C. If Assertion is True but the Reason is Flase.
D. If both Assertion & Reason are false.

Answer

To solve the question, we need to analyze both the assertion and the reason provided.

### Step-by-Step Solution:

1. **Understanding the Assertion**:
- The assertion states that for sequencing, the total DNA from a cell is isolated and converted into random fragments.
- This is true because during DNA sequencing processes, especially in large projects like the Human Genome Project, DNA is indeed fragmented to facilitate sequencing.

2. **Understanding the Reason**:
- The reason states that DNA is a long polymer and there are technical limitations in sequencing very long pieces of DNA.
- This is also true. DNA molecules can be extremely long, and current sequencing technologies have limitations when it comes to reading long sequences in one go.

3. **Connecting the Assertion and Reason**:
- The assertion is true because it reflects the methodology used in sequencing, while the reason is true as it explains why this methodology is necessary.
- The reason provides a valid explanation for the assertion, as the fragmentation of DNA is a direct response to the technical challenges posed by the length of DNA.

4. **Conclusion**:
- Since both the assertion and the reason are true, and the reason correctly explains the assertion, we conclude that the correct answer is that both the assertion and reason are true, and the reason is the correct explanation of the assertion.

### Final Answer:
Both assertion and reason are true, and the reason is the correct explanation of the assertion.

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