Assertion :- BAC & YAC are the common vectors used in HGP.
Reason : In HGP, sequencing was done by automated DNA
sequences that worked on methods of F. Sanger.

Options

A. If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion.
B. If both Assertion & Reason are trur but Reason is not a correct explanation of the Assertion.
C. If Assertion is True but the Reason is Flase.
D. If both Assertion & Reason are false.

Answer

**Step-by-Step Solution:**

1. **Understanding the Assertion:**
- The assertion states that BAC (Bacterial Artificial Chromosomes) and YAC (Yeast Artificial Chromosomes) are common vectors used in the Human Genome Project (HGP).
- This is true because both BACs and YACs are utilized in cloning large fragments of DNA, which is essential for sequencing the human genome.

2. **Understanding the Reason:**
- The reason states that sequencing in the HGP was done using automated DNA sequencers based on the methods developed by Frederick Sanger.
- This is also true as the Sanger sequencing method was a key technology used in the HGP for determining the nucleotide sequences of DNA.

3. **Evaluating the Relationship Between Assertion and Reason:**
- Both the assertion and reason are true statements.
- However, the reason does not directly explain the assertion. The use of BACs and YACs as vectors is independent of the sequencing method used, which means that while both statements are true, one does not explain the other.

4. **Choosing the Correct Option:**
- Given that both the assertion and reason are true but the reason is not the correct explanation of the assertion, the correct answer is option B: "Both assertion and reason are true but reason is not the correct explanation of the assertion."

**Final Answer:**
B - Both assertion and reason are true but reason is not the correct explanation of the assertion.

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