Histone is a basic protein due to

Options

A. alanine & glycine
B. methionine & serine
C. tryptophan & tyrosine
D. lysine & arginine

Answer

**Step-by-Step Solution:**

1. **Understanding Histones**: Histones are proteins that are found in the nucleus of eukaryotic cells. They play a crucial role in the packaging and organization of DNA.

2. **Basic Nature of Histones**: Histones are classified as basic proteins. This means they have a higher pH and are alkaline in nature.

3. **Charge Interaction**: The basic nature of histones allows them to carry a positive charge. This positive charge is essential for their interaction with negatively charged DNA, facilitating the binding of histones to DNA.

4. **Amino Acids Responsible for Basicity**: The basic nature of histones is primarily due to the presence of specific amino acids. The two key amino acids that contribute to this basicity are:
- **Lysine**: Contains two amino groups and one carboxylic group, contributing to its positive charge.
- **Arginine**: Also contains multiple amino groups, which similarly contribute to its basic nature.

5. **Evaluating Options**: Given the options provided, we can evaluate:
- **Option 1**: Alanine and Glycine - Incorrect, as these are not basic amino acids.
- **Option 2**: Methionine and Serine - Incorrect, as these do not contribute to the basicity of histones.
- **Option 3**: Tryptophan and Tyrosine - Incorrect, as these are neutral amino acids.
- **Option 4**: Lysine and Arginine - Correct, as both are basic amino acids that contribute to the positive charge of histones.

6. **Conclusion**: Therefore, the correct answer is that histone is a basic protein due to the presence of lysine and arginine.

**Final Answer**: Histone is a basic protein due to the presence of lysine and arginine.

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